The European Colorectal Cancer Working Groups offer an excellent infrastructure for the performance of multicentre clinical studies in patients with colorectal cancer. Examples are the TME, PROCTOR/SCRIPT, and CAIRO studies. The success of these studies is largely due to the collaboration between the relevant groups and disciplines, such as surgery, radiotherapy, medical oncology, and pathology, as well as the support from data centres such as the regional trial offices of the Comprehensive Cancer Centres. This allows the conduct of large randomized studies with
objectives that are in favor of the treatment of colorectal cancer patients. The primary goal of the EMCCC is to exchange clinal data to improve the quality of diagnosis and treatment of patients with colorectal cancer on an international level.